Developmental changes of histidine decarboxylase (HDC) and dopa decarboxylase (DDC) in fetus rat liver
نویسندگان
چکیده
منابع مشابه
Spectroscopic analysis of recombinant rat histidine decarboxylase.
Mammalian histidine decarboxylases have not been characterized well owing to their low amounts in tissues and instability. We describe here the first spectroscopic characterization of a mammalian histidine decarboxylase, i.e. a recombinant version of the rat enzyme purified from transformed Escherichia coli cultures, with similar kinetic constants to those reported for mammalian histidine decar...
متن کاملRat Liver Aminomalonate Decarboxylase
Studies on the aminomalonate decarboxylase of rat liver indicate that this activity is a property of cytoplasmic serine hydroxymethylase. Thus, throughout purification of the enzyme, aminomalonate decarboxylase, serine hydroxymethylase and allothreonine aldolase exhibited the same relative activities. Competition between the several substrates was observed and resolution of the enzyme by treatm...
متن کاملDeletion of histidine decarboxylase (HDC) enhances the antinociceptive effects of orexin A in the central nervous system
It has long been established that histamine plays a role as a mediator of inflammation. From numerous studies, it has been well known that the amine has many pharmacological actions on a variety of organs. To evaluate the role of histamine in pain perception, we generated HDC knockout mice using a gene targeting method. Histamine is a hydrophilic autacoid, and in most tissues it is stored and s...
متن کاملDeletion of histidine decarboxylase (HDC) enhances the antinociceptive effects of orexin A in the central nervous system
It has long been established that histamine plays a role as a mediator of inflammation. From numerous studies, it has been well known that the amine has many pharmacological actions on a variety of organs. To evaluate the role of histamine in pain perception, we generated HDC knockout mice using a gene targeting method. Histamine is a hydrophilic autacoid, and in most tissues it is stored and s...
متن کاملCoexistence of adenosine deaminase, histidine decarboxylase, and glutamate decarboxylase in hypothalamic neurons of the rat.
Neurons immunoreactive for the enzyme adenosine deaminase (ADA) in the posterior basal hypothalamus of the rat have a distribution pattern similar to those immunoreactive for histidine decarboxylase (HDC) and are particularly numerous in the tuberal (TM), caudal (CM) and postmammillary caudal (PCM) hypothalamic magnocellular nuclei which harbor neurons containing glutamic acid decarboxylase (GA...
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ژورنال
عنوان ژورنال: Japanese Journal of Pharmacology
سال: 1989
ISSN: 0021-5198
DOI: 10.1016/s0021-5198(19)56509-x